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Fighting Cystitis & UTIs with D-Mannose
Interstitial Cystitis - a way forward
Our experience has shown us that Waterfall D-Mannose is not effective against every type of interstitial cystitis. However, it does seem to work for some people. Interstitial cystitis can have many causes, one of which is related to previous infections, and although the urine can be clear, there can be remnants of E.coli bio-molecularly attached, though dead, to cells of the bladder, or buried in the walls of the bladder.
Originally, we were very doubtful whether the product would work for interstitial cystitis at all but the results the product is achieving have helped change our minds on this subject. That said, the mechanism of how D-Mannose works on interstitial cystitis is not clearly understood. It's hard to believe that something so simple as pure Waterfall D-Mannose can solve a problem when medical science, experience, and expertise have all failed to provide a satisfactory or lasting solution.
The mechanism remains uncertain, but
the bio-molecular attraction of the E.coli lectins for mannose may tell
part, or even most of the story. And logically, the E.coli don't have
to be whole, or still alive for that bio-molecular attraction and attachment
to take place. What we would say is that it is well worth trying Waterfall D-Mannose for this condition, and it certainly can't do any harm. It is
not always a fast fix for sufferers of interstitial cystitis, but as part
of a long term strategy it won't do any harm and may just surprise you.
We've had some people with interstitial cystitis say Waterfall D-Mannose is the only thing that has brought them relief after many years of suffering.
One customer has made it very clear that Waterfall D-Mannose is the only
reason he has not killed himself. That's a bit too intense for us - we
don't want our product to mean life or death. What if we missed a post
or something?
But it really saddens us when it doesn't work for everyone - it's not a panacea.
Other sufferers have told us that the relief with Waterfall D-Mannose was almost immediate, which leads us to suspect that they may have been wrongly diagnosed with interstitial cystitis, and probably had a low level of infection, which was causing the pain, but was not considered enough of an infection to treat with antibiotics.
Labs often do not consider you to have
an infection if a urine test shows you to have less than less than 10,000
E.coli per cubic millilitre. However, E.coli can double their colony size
every 20 minutes in the right conditions (for example if you have conditioned
them with cranberry).
The other option to explain the relief is the possible cleansing effect
of Waterfall D-Mannose on the bladder, combined with the D-Mannose known
anti-inflammatory properties*. After taking the product for 2 to 3 months,
most bladders are very close to being completely back to normal, whether
the problem has been bacterial or interstitial.
* from www.invista.com: "Mannose stimulates fibroblasts to make more collagen and proteoglycans, which means that healing is speeded up, pain is lessened, and skin integrity returns to normal faster. Mannose also works to correct over-active neutrophils (T cells) that cause misguided inflammation. Researchers in Australia have confirmed this action. "
We got this message from a sufferer:
"I've had interstitial cystitis for nine years, with all the worst of the symptoms. I've never heard of anyone who had it as bad as me. I had all of this incredible pain and it got to the point where I couldn't even go out of the house. I was on permanent antibiotics for ages, but they didn't seem to do any good, and I've been probed, prodded, stretched, injected, and flushed out (agonising) so many times that it got to the point where I was living in permanent agony. Anyway, my doctor referred me to a new consultant, and after a look through my notes, he casually said, 'I think the best thing we can do is whip your bladder out.' I was appalled, and just ran out of the office crying. When I got home, I started searching online, and found your wonderful product. I was sceptical, because I've tried so many different remedies before, but when you've got so much pain, you are willing to try anything. I couldn't believe it! Within a couple of hours of starting with Waterfall D-Mannose, I realised that the pain was disappearing. By the third day, I felt better than I've felt in years. Now I get the occasional bad day when I have to take heaps of the sweet cure to control the problem which is obviously still hovering around, but basically I've got my life back, and I'm keeping my bladder which is now functioning perfectly well thank you... I'm telling everyone I meet, and I'm taking the doctor your information to show him. I'm on a mission now! People are not going to get their bladders 'whipped' out if I can help it. Thank you, thank you, thank you." Aime
The following extract is from a 6 month clinical trial of D-Mannose, this part directly concerning sufferers of interstitial cystitis: Abstracted from a study by Michael Blue, M.D., Urologist (Norman, OK).
"Those females who were not confirmed by culture to have bacterial UTI but had UTI-associated symptoms were classified into a painful-bladder-syndrome (PBS) group. Of the 18 PBS females who were treated daily with two scoops of D-Mannose, 17 (94%) reported symptom improvement, the lone exception being a subject unable to be contacted, but also not returning for treatment. Eighty percent became totally symptom free."
Currently, Waterfall D-Mannose is undergoing clinical trials in Italy for use against Interstitial Cystitis. The study by a well known urologist and researcher, Dr Daniele Porru is still in progress. His interim report is "So far, I’ve had positive feedback from various patients... Significant side effects (gastroenteric or other kind) have not been reported."
Once you have successfully dealt with an episode of cystitis using Waterfall D-Mannose, you can use it to keep infections at bay. In most cases it will be more effective than a prophylactic antibiotic, both as a preventative, and if necessary, to stop flare-ups from developing into full blown infections.
Aquire D-Mannose
This page is based on our own experience and information from our customers. Some of what we say here is based on our best guess of what is happening. We try to provide information that is accurate, but nothing we say here should be considered medical advice. This is for people who have explored the medical options and are looking for another way forward. Waterfall D-Mannose™ is an exceptionally effective alternative remedy. We are advising you how best to use that alternative remedy. Please see your doctor for medical advice.